Ph.D. Student Plant Genome Editing
Job description
The Plant Molecular Physiology lab at University of Florida, headed by Professor Fredy Altpeter, is seeking a highly motivated Ph.D. student with experience in plant tissue culture and genetic engineering and molecular biology to join our team. The research program focuses on genome editing and metabolic engineering of sugarcane to improve crop performance and quality.
The successful candidate will apply existing CRISPR‐Cas9 systems to validate targets for crop improvement, develop genome editing strategies that do not leave a transgenic footprint in vegetatively propagated sugarcane, and characterize genetically modified events similar in scope to our recent publications: https://www.ncbi.nlm.nih.gov/pubmed/27306903; http://onlinelibrary.wiley.com/doi/10.1111/pbi.12411/epdf; http://onlinelibrary.wiley.com/doi/10.1111/pbi.12833/full.
Hands-on experience with plant tissue culture and genetic transformation is essential. The ideal candidate will also be experience with vector construction, molecular and phenotypic characterization of transgenic plants. This work requires excellent interpersonal and communication skills in English as well as excellent writing skills as demonstrated by a strong publication record in peer reviewed journals.
Please email your resume, cover letter, GRE scores, GPA, and contact information of three references to the PI, altpeter@ufl.edu. The University of Florida is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, national origin, religion, sex, gender identity, age, sexual orientation, genetic information, status as an individual with a disability, or status as a protected veteran. Stipend will be competitive and includes benefits.
Application review will continue until a suitable candidate is identified. Start date is flexible.
Selected publications related to this position:
- Parajuli, S., Kannan, B., Karan, R., Liu, H., Garcia-Ruiz, E., Kumar, D., Singh, V., Zhao, H., Long, S.P., Shanklin, J., Altpeter, F. March 21, 2020. “Towards Oilcane: Engineering Hyperaccumulation of Triacylglycerol into Sugarcane Stems.” GCB Bioenergy. DOI: 10.1111/gcbb.12684. https://onlinelibrary.wiley.com/doi/full/10.1111/gcbb.12684
- Kannan, B., Jung, J.H., Moxley, G. W., Lee, S.‐M. Altpeter, F. 2017. TALEN mediated targeted mutagenesis of more than 100 COMT copies/alleles in highly polyploid sugarcane improves saccharification efficiency without compromising biomass yield. Plant Biotechn. J. (in press). http://onlinelibrary.wiley.com/doi/10.1111/pbi.12833/full
- Altpeter F. et al. 2016. Advancing Crop Transformation in the Era of Genome Editing. Plant Cell. 28: 1510‐1520. http://www.plantcell.org/content/early/2016/06/22/tpc.16.00196.full.pdf+html
- Jung, J. H. and F. Altpeter. 2016. TALEN mediated targeted mutagenesis of the caffeic acid O‐methyltransferase in highly polyploid sugarcane improves cell wall composition for production of bioethanol. Plant. Mol. Biol. 92: 131‐142. https://www.ncbi.nlm.nih.gov/pubmed/27306903
- Zale, J., J.H. Jung, J.Y. Kim, B, B. Patha, R. Karan, H. Liu, X. Chen, H. Wu, J. Candreva, Z. Zhai, J. Shanklin, F. Altpeter. 2016. Metabolic engineering of sugarcane to accumulate energy‐dense triacylglycerols in vegetative biomass. Plant Biotech. J. 14: 661‐669. http://onlinelibrary.wiley.com/doi/10.1111/pbi.12411/epdf
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